Thyroid Function (TSH, fT4)
TSH does the primary screening, with free T4 added once TSH returns abnormal. Thyroid hormone sets metabolic rate, so disease in either direction reaches into weight, mood, cardiovascular and bone health, and subclinical disease is genuinely common — especially in older women. The question is not whether the test works. It is whether finding subclinical disease in someone who feels well leads anywhere useful.
Testing is well-evidenced and clearly indicated once symptoms, goitre or risk factors are present — postpartum, autoimmune disease, family history, amiodarone or lithium use. Screening asymptomatic non-pregnant adults is a separate question, and the US Preventive Services Task Force’s 2004 recommendation statement found the evidence insufficient to recommend for or against it (Grade I): fair evidence that TSH detects subclinical disease, poor evidence that treating screen-detected cases improves outcomes. A 2015 update reached materially the same conclusion.
US Preventive Services Task Force. Ann Intern Med. 2004. PubMed: PMID 14734336 · Full cost breakdown & who should test →
Singapore pricing. We have a full price breakdown for this test, using checked 2026 figures from named providers — read the price guide →